FDA reports are based on 4.4 million reports submitted to the FDA's MedWatch from January 1, 2004, to December 31, 2012. These contain 5.9 million suspected drugs, suspected of causing 16.5 million side effects. About a third of these reports come from outside the United States. Health Canada reports are based on 320,172 reports submitted to the Canada Vigilance Adverse Reaction Online Database from January 1, 1965, to September 30, 2012. These contain 363,492 suspected drugs, suspected of causing 865,826 side effects.